Ryan Bregante smiling with Klinefelter syndrome and 47 xxy

Spreading positivty and awareness for Klinefelter syndrome.

My name is Ryan Bregante, I was born with Klinefelter syndrome.

here's what matters

The Faces of Klinefelter Syndrome

These are the Real People who are helping us make a difference.

Xxy Employment

Extraordinary people around the world with not just any ordinary job.

Testosterone Replacement Therapy

All of the current information on different options for treatment.

Our Positive Traits

An amazing set of traits being born with XXY. These things are defiantly worth smiling about.

Clinical Trials

Sign up for clinical trials with X & Y variations to help make a difference.

Helping You

We know you have so many questions. This is our community working together to answer them for you.

Klinefelter syndrome Athletes

Our community shares what types of sports they play and enjoy.

Education after High School

School can be extremely tough for many. Here are their accomplishments after high school.

Valuable resources

Here is a list of nonprofits, clinics, hospitals and other helpful resources.

Our Youtube Channel

Come learn more about living with Klinefelter syndrome. Real interviews with parents, kids, and adults.

Our Community Blog

Read the inspiring stories of our community members.

Parents guide to 47 XXY

Parents guide to 47 XXY was written by a mother who found out prenatally. This guide is extremely helpful.

Did you know

Klinefelter syndrome is a chromosomal variation in boys and men that can affect physical and intellectual development. Its signs and symptoms vary among affected individuals. In some cases, the features of the condition are so mild that the condition is not diagnosed until puberty or adulthood, and researchers believe that some affected men and boys are never diagnosed. Klinefelter syndrome affects 1 in 500 to 1,000 newborn boys. It is among the most common sex chromosome disorders. that they present with a range spectrum one size fits all.

08 Oct

My Son’s Klinefelter Story

Ryan Bregante no responses

English translation from Spanish I wanted to have an amniocentesis. Although you do it by ...

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01 Oct

Mexican Mother’s 47 XXY Story

Ryan Bregante no responses

English translation from Spanish. On June 30, 2008, they called us on the phone to ...

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24 Sep

Spanish Mother’s 47 XXY Story

Ryan Bregante no responses

English translation from Spanish. It has been many years since I wrote this message in ...

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Testosterone Replacement therapy, livingwithxxy, xxy, Klinefelter syndrome
30 Aug

Testosterone Replacement Therapy

Ryan Bregante 2 responses

In January of 2018 I was invited to speak in front of the FDA in ...

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47 XXY syndrome
30 Jul

47 XXY Syndrome Awareness

Ryan Bregante no responses

To my surprise, I found out I was pregnant at 45. My husband & I ...

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Mom holding 47xxy mosaic baby diagnosed by OBGYN
23 Jul

OBGYN Diagnosed Mosaic 47 xxy

Ryan Bregante one response

Another wonderful story here.  May 8th, 2017 is a day I will never forget. It ...

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What they say